{"id":15098,"date":"2018-02-22T17:40:00","date_gmt":"2018-02-22T17:40:00","guid":{"rendered":"http:\/\/associatednews.us\/content\/2018\/02\/22\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early\/"},"modified":"2018-02-22T17:40:00","modified_gmt":"2018-02-22T17:40:00","slug":"synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early","status":"publish","type":"post","link":"https:\/\/associatednews.us\/content\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early\/","title":{"rendered":"Synergy Between Nurses And Automation Could Be Key To Finding Sepsis Early"},"content":{"rendered":"<p><span style=\"font-style:italic;font-size:16px\">By  <a class=\"colorbox\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2018\/02\/22\/583846656\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early?utm_medium=RSS&amp;utm_campaign=healthcare\">Richard Harris<\/a><\/span>  <\/p>\n<div class=\"ftpimagefix\" style=\"float:left\"><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2018\/02\/22\/583846656\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early?utm_medium=RSS&amp;utm_campaign=healthcare\"><img decoding=\"async\" width=\"150\" src=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1100-c15.jpg\" alt><\/p>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1200.jpg\"><\/a><\/div>\n<div>\n<div>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1200.jpg\">Enlarge this image<\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                Rosemary Grant is a registered nurse and helps coordinate sepsis care at Harborview Medical Center in Seattle. The center&#8217;s goal, she says, is to get a patient who might be developing sepsis antibiotics within three hours.<\/p>\n<p>                <b><\/p>\n<p>                    Ian C. Bates for NPR<\/p>\n<p>                <\/b><b><b>hide caption<\/b><\/b><\/p>\n<\/div>\n<p><b><b>toggle caption<\/b><\/b><\/div>\n<p><span><\/p>\n<p>        Ian C. Bates for NPR<\/p>\n<p>    <\/span><\/div>\n<\/div>\n<p>A quarter of a million Americans die every year from sepsis, which is the body&#8217;s reaction to overwhelming infection. This cascade of organ failure can be nipped in the bud if health care workers know it&#8217;s ramping up, but that&#8217;s often not easy to do.<\/p>\n<p>&#8220;Sepsis is a really frustrating disease,&#8221; says <a class=\"colorbox\" rel=\"nofollow\" href=\"http:\/\/depts.washington.edu\/pulmcc\/directory\/bio\/carlbom.html\">Dr. David Carlbom<\/a>, a critical care pulmonologist, and medical director of the sepsis program at the Harborview Medical Center in Seattle. &#8220;There&#8217;s no blood test for sepsis,&#8221; he says. &#8220;There&#8217;s nothing you can look at under the microscope and say &#8216;this is sepsis.&#8217; &#8220;<\/p>\n<p>So a few years ago, Carlbom set out to devise a system that uses more subtle clues from a patient&#8217;s day-to-day electronic health records to send up warning flags of impending sepsis.<\/p>\n<p><!-- END ID=\"RES587659180\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The automated system looks for patterns in symptoms like high temperature, low temperature, low blood pressure, fast breathing and high white-blood-cell counts. No single symptom signals sepsis, but certain patterns suggest this condition could be emerging.<\/p>\n<p>Rosemary Grant, a registered nurse who coordinates sepsis care at Harborview, explains how it works as we stand at a nursing station in the hospital.<\/p>\n<p>The previous day, a red box appeared on a computer screen next to the name of a patient who had been hospitalized for several weeks following a motorcycle accident. The computer prompted the nurse responsible for that patient to assess whether his constellation of symptoms was an early sign of sepsis.<\/p>\n<p>&#8220;If the nurse says yes, then the provider is automatically paged, out of the computer system,&#8221; Grant says.<\/p>\n<aside>\n<div><\/div>\n<\/aside>\n<aside>\n<div><\/div>\n<\/aside>\n<p>The doctor is supposed to respond within half an hour, she says, and the overall goal is to get a patient who might be developing sepsis antibiotics within three hours.<\/p>\n<p>But faster breathing might also be due to a walk down the corridor, and having an elevated number of white blood cells is not a reliable sepsis indicator in someone with cancer. Given the general nature of these symptoms, most of the time the nurse will report that the alert is just a false alarm.<\/p>\n<p>Once one alarm is triggered, nurses aren&#8217;t notified again for 12 hours, Grant adds \u2014 and that helps reduce the number of annoying false alarms the hospital staff must handle.<\/p>\n<p>If the nurse says it&#8217;s not sepsis, Grant says, &#8220;then the computer system just asks &#8216;why do you think the patient has these abnormal vital signs?&#8217; &#8220;<\/p>\n<p>The nurse may type in that the patient&#8217;s heart rate was up because he was exercising, or has a high pulse because she&#8217;s in pain. It&#8217;s a partnership between the automation and the human being. And while systems like this are increasingly common in hospitals, the synergy between nurses and computers is a hallmark of the Seattle program.<\/p>\n<p>&#8220;Just having the nurses really being in tune with their patients is really what makes the system work,&#8221; Grant says. And it <em>is<\/em> working, she says. Since the system was installed in 2011 \u2014 and updated in 2017 \u2014 hospital mortality has fallen.<\/p>\n<p>We head over to the room of the injured 34-year-old motorcyclist to see how he&#8217;s doing. Matthew Clark says his world changed on Jan. 15, when he had an unfortunate encounter with a car.<\/p>\n<p>&#8220;I was just on the way to make some chicken chili for my girlfriend,&#8221; he says, &#8220;and a young distracted driver who wasn&#8217;t looking kind of plowed into me.&#8221; Two big bones in his left leg were broken, requiring a series of operations to set right.<\/p>\n<p>But nine days after the accident, Clark got a clue his recovery was taking a turn for the worse when a friend came into his hospital room and he had trouble waving to her.<\/p>\n<p>&#8220;I noticed my hands were shaking,&#8221; he says, &#8220;and my blood started to leave my hands and feet. I just looked at her and said &#8216;I need some help.&#8217; &#8220;<\/p>\n<p>The hospital&#8217;s internal 911 system responded with a team that, among other things, provided intravenous antibiotics to prevent his apparent infection from raging out of control and becoming septic shock.<\/p>\n<p>&#8220;My temperature dropped incredibly,&#8221; he says. &#8220;I&#8217;d never been so cold or shook so hard in my life.&#8221;<\/p>\n<p>And 24 hours later, he says, he was back to his old self.<\/p>\n<p>In this case, the patient&#8217;s alert actually popped up on the computer screen long after the medical team had stepped in.<\/p>\n<div>\n<div><img decoding=\"async\" src=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/12\/david-carlbaum-1_custom-807c0bb7daa9e9313dd11ed3298d5907c532c1de-s1100-c15.jpg\" alt><\/p>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/12\/david-carlbaum-1_enl-f80fdebc4f40e5360a44672878a38926449d0af6-s1200.jpg\">Enlarge this image<\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                Dr. David Carlbom, a critical care pulmonologist at UW Medicine&#8217;s Harborview Medical Center, says sepsis has long frustrated clinicians. &#8220;There&#8217;s no blood test,&#8221; he says. &#8220;There&#8217;s nothing you can look at under the microscope and say &#8216;this is sepsis.&#8217; &#8221;<\/p>\n<p>                <b><\/p>\n<p>                    Ian C. Bates for NPR<\/p>\n<p>                <\/b><b><b>hide caption<\/b><\/b><\/p>\n<\/div>\n<p><b><b>toggle caption<\/b><\/b><\/div>\n<p><span><\/p>\n<p>        Ian C. Bates for NPR<\/p>\n<p>    <\/span><\/div>\n<\/div>\n<p>&#8220;I think his case is a great example of action happening before the computer catches up,&#8221; Carlbom says. &#8220;The vital signs are measured and dealt with at the bedside before they&#8217;re entered into the computer.&#8221;<\/p>\n<p>In fact, that need to enter vital signs manually into the electronic medical record is a shortcoming of this system. The computer may be ever vigilant for signs of infection, but it only gets new data to crunch a few times a day.<\/p>\n<p><!-- END ID=\"RES584565871\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>This isn&#8217;t simply an issue for the system at Harborview \u2014 it&#8217;s a shortcoming for automated sepsis-detection programs elsewhere. Medical researchers are actively working to close that gap, says <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/hdsi.uchicago.edu\/faculty-innovators\/matthew-churpek-md\/\">Dr. Matthew Churpek<\/a> at the University of Chicago.<\/p>\n<p>&#8220;We&#8217;re partnering now with a company that has a device that goes under a patient&#8217;s mattress and can continuously calculate their heart rate and respiratory rate in real time,&#8221; Churpek says.<\/p>\n<p>His team and others are also working on more accurate computer algorithms, to reduce the number of false alarms that are a problem both in Seattle and in similar systems around the country.<\/p>\n<p>Doctors have struggled to find a good treatment for sepsis. For example, last year Dr. Paul Marik announced that a protocol involving intravenous vitamin C, thiamine and steroids dramatically reduced the number of sepsis deaths in his hospital&#8217;s intensive care unit in Norfolk, Va. That unproven treatment has just begun to be studied in a series of careful clinical trials.<\/p>\n<p>Carlbom uses that experimental therapy sometimes, but says it would be much better to prevent the condition.<\/p>\n<p>&#8220;We use all these therapies in the ICU as a rescue tool when people are very sick dying of septic shock,&#8221; he says, &#8220;but I think early discovery will probably affect mortality more.&#8221;<\/p>\n<p><em>You can contact Richard Harris via email: <\/em><a class=\"colorbox\" rel=\"nofollow\" href=\"mailto:rharris@npr.org\">rharris@npr.org<\/a>.<em><\/em><\/p>\n<p><strong><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/\">Let&#8217;s block ads!<\/a><\/strong> <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/acceptable.html\">(Why?)<\/a><\/p>\n<p>Source:: <a href=\"https:\/\/www.npr.org\/sections\/health-shots\/2018\/02\/22\/583846656\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early?utm_medium=RSS&amp;utm_campaign=healthcare\" class=\"colorbox\" title=\"Synergy Between Nurses And Automation Could Be Key To Finding Sepsis Early\" rel=\"nofollow\">https:\/\/www.npr.org\/sections\/health-shots\/2018\/02\/22\/583846656\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early?utm_medium=RSS&amp;utm_campaign=healthcare<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"ftpimagefix\" style=\"float:left\"><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2018\/02\/22\/583846656\/synergy-between-nurses-and-automation-could-be-key-to-finding-sepsis-early?utm_medium=RSS&amp;utm_campaign=healthcare\"><img decoding=\"async\" width=\"150\" src=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1100-c15.jpg\" alt><\/p>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1200.jpg\"><\/a><\/div>\n<div>\n<div>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/20\/sepsis-rosemary-4-62a34f4138c1ba02ab5dc583305cb2f5cf5077d7-s1200.jpg\">Enlarge this image<\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                Rosemary Grant is a registered nurse and helps coordinate sepsis care at Harborview Medical Center in Seattle. The center&#8217;s goal, she says, is to get a patient who might be developing sepsis antibiotics within three hours.<\/p>\n<p>                <b><\/p>\n<p>                    Ian C. Bates for NPR<\/p>\n<p>                <\/b><b><b>hide caption<\/b><\/b><\/p>\n<\/div>\n<p><b><b>toggle caption<\/b><\/b><\/div>\n<p><span><\/p>\n<p>        Ian C. Bates for NPR<\/p>\n<p>    <\/span><\/div>\n<\/div>\n<p>A quarter of a million Americans die every year from sepsis, which is the body&#8217;s reaction to overwhelming infection. This cascade of organ failure can be nipped in the bud if health care workers know it&#8217;s ramping up, but that&#8217;s often not easy to do.<\/p>\n<p>&#8220;Sepsis is a really frustrating disease,&#8221; says <a class=\"colorbox\" rel=\"nofollow\" href=\"http:\/\/depts.washington.edu\/pulmcc\/directory\/bio\/carlbom.html\">Dr. David Carlbom<\/a>, a critical care pulmonologist, and medical director of the sepsis program at the Harborview Medical Center in Seattle. &#8220;There&#8217;s no blood test for sepsis,&#8221; he says. &#8220;There&#8217;s nothing you can look at under the microscope and say &#8216;this is sepsis.&#8217; &#8220;<\/p>\n<p>So a few years ago, Carlbom set out to devise a system that uses more subtle clues from a patient&#8217;s day-to-day electronic health records to send up warning flags of impending sepsis.<\/p>\n<p><!-- END ID=\"RES587659180\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The automated system looks for patterns in symptoms like high temperature, low temperature, low blood pressure, fast breathing and high white-blood-cell counts. No single symptom signals sepsis, but certain patterns suggest this condition could be emerging.<\/p>\n<p>Rosemary Grant, a registered nurse who coordinates sepsis care at Harborview, explains how it works as we stand at a nursing station in the hospital.<\/p>\n<p>The previous day, a red box appeared on a computer screen next to the name of a patient who had been hospitalized for several weeks following a motorcycle accident. The computer prompted the nurse responsible for that patient to assess whether his constellation of symptoms was an early sign of sepsis.<\/p>\n<p>&#8220;If the nurse says yes, then the provider is automatically paged, out of the computer system,&#8221; Grant says.<\/p>\n<aside>\n<div><\/div>\n<\/aside>\n<aside>\n<div><\/div>\n<\/aside>\n<p>The doctor is supposed to respond within half an hour, she says, and the overall goal is to get a patient who might be developing sepsis antibiotics within three hours.<\/p>\n<p>But faster breathing might also be due to a walk down the corridor, and having an elevated number of white blood cells is not a reliable sepsis indicator in someone with cancer. Given the general nature of these symptoms, most of the time the nurse will report that the alert is just a false alarm.<\/p>\n<p>Once one alarm is triggered, nurses aren&#8217;t notified again for 12 hours, Grant adds \u2014 and that helps reduce the number of annoying false alarms the hospital staff must handle.<\/p>\n<p>If the nurse says it&#8217;s not sepsis, Grant says, &#8220;then the computer system just asks &#8216;why do you think the patient has these abnormal vital signs?&#8217; &#8220;<\/p>\n<p>The nurse may type in that the patient&#8217;s heart rate was up because he was exercising, or has a high pulse because she&#8217;s in pain. It&#8217;s a partnership between the automation and the human being. And while systems like this are increasingly common in hospitals, the synergy between nurses and computers is a hallmark of the Seattle program.<\/p>\n<p>&#8220;Just having the nurses really being in tune with their patients is really what makes the system work,&#8221; Grant says. And it <em>is<\/em> working, she says. Since the system was installed in 2011 \u2014 and updated in 2017 \u2014 hospital mortality has fallen.<\/p>\n<p>We head over to the room of the injured 34-year-old motorcyclist to see how he&#8217;s doing. Matthew Clark says his world changed on Jan. 15, when he had an unfortunate encounter with a car.<\/p>\n<p>&#8220;I was just on the way to make some chicken chili for my girlfriend,&#8221; he says, &#8220;and a young distracted driver who wasn&#8217;t looking kind of plowed into me.&#8221; Two big bones in his left leg were broken, requiring a series of operations to set right.<\/p>\n<p>But nine days after the accident, Clark got a clue his recovery was taking a turn for the worse when a friend came into his hospital room and he had trouble waving to her.<\/p>\n<p>&#8220;I noticed my hands were shaking,&#8221; he says, &#8220;and my blood started to leave my hands and feet. I just looked at her and said &#8216;I need some help.&#8217; &#8220;<\/p>\n<p>The hospital&#8217;s internal 911 system responded with a team that, among other things, provided intravenous antibiotics to prevent his apparent infection from raging out of control and becoming septic shock.<\/p>\n<p>&#8220;My temperature dropped incredibly,&#8221; he says. &#8220;I&#8217;d never been so cold or shook so hard in my life.&#8221;<\/p>\n<p>And 24 hours later, he says, he was back to his old self.<\/p>\n<p>In this case, the patient&#8217;s alert actually popped up on the computer screen long after the medical team had stepped in.<\/p>\n<div>\n<div><img decoding=\"async\" src=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/12\/david-carlbaum-1_custom-807c0bb7daa9e9313dd11ed3298d5907c532c1de-s1100-c15.jpg\" alt><\/p>\n<div><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2018\/02\/12\/david-carlbaum-1_enl-f80fdebc4f40e5360a44672878a38926449d0af6-s1200.jpg\">Enlarge this image<\/a><\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                Dr. David Carlbom, a critical care pulmonologist at UW Medicine&#8217;s Harborview Medical Center, says sepsis has long frustrated clinicians. &#8220;There&#8217;s no blood test,&#8221; he says. &#8220;There&#8217;s nothing you can look at under the microscope and say &#8216;this is sepsis.&#8217; &#8221;<\/p>\n<p>                <b><\/p>\n<p>                    Ian C. Bates for NPR<\/p>\n<p>                <\/b><b><b>hide caption<\/b><\/b><\/p>\n<\/div>\n<p><b><b>toggle caption<\/b><\/b><\/div>\n<p><span><\/p>\n<p>        Ian C. Bates for NPR<\/p>\n<p>    <\/span><\/div>\n<\/div>\n<p>&#8220;I think his case is a great example of action happening before the computer catches up,&#8221; Carlbom says. &#8220;The vital signs are measured and dealt with at the bedside before they&#8217;re entered into the computer.&#8221;<\/p>\n<p>In fact, that need to enter vital signs manually into the electronic medical record is a shortcoming of this system. The computer may be ever vigilant for signs of infection, but it only gets new data to crunch a few times a day.<\/p>\n<p><!-- END ID=\"RES584565871\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>This isn&#8217;t simply an issue for the system at Harborview \u2014 it&#8217;s a shortcoming for automated sepsis-detection programs elsewhere. Medical researchers are actively working to close that gap, says <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/hdsi.uchicago.edu\/faculty-innovators\/matthew-churpek-md\/\">Dr. Matthew Churpek<\/a> at the University of Chicago.<\/p>\n<p>&#8220;We&#8217;re partnering now with a company that has a device that goes under a patient&#8217;s mattress and can continuously calculate their heart rate and respiratory rate in real time,&#8221; Churpek says.<\/p>\n<p>His team and others are also working on more accurate computer algorithms, to reduce the number of false alarms that are a problem both in Seattle and in similar systems around the country.<\/p>\n<p>Doctors have struggled to find a good treatment for sepsis. For example, last year Dr. Paul Marik announced that a protocol involving intravenous vitamin C, thiamine and steroids dramatically reduced the number of sepsis deaths in his hospital&#8217;s intensive care unit in Norfolk, Va. That unproven treatment has just begun to be studied in a series of careful clinical trials.<\/p>\n<p>Carlbom uses that experimental therapy sometimes, but says it would be much better to prevent the condition.<\/p>\n<p>&#8220;We use all these therapies in the ICU as a rescue tool when people are very sick dying of septic shock,&#8221; he says, &#8220;but I think early discovery will probably affect mortality more.&#8221;<\/p>\n<p><em>You can contact Richard Harris via email: <\/em><a class=\"colorbox\" rel=\"nofollow\" href=\"mailto:rharris@npr.org\">rharris@npr.org<\/a>.<em><\/em><\/p>\n<p><strong><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/\">Let&#8217;s block ads!<\/a><\/strong> <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/acceptable.html\">(Why?)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-15098","post","type-post","status-publish","format-standard","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts\/15098","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/comments?post=15098"}],"version-history":[{"count":0,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts\/15098\/revisions"}],"wp:attachment":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/media?parent=15098"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/categories?post=15098"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/tags?post=15098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}