{"id":20182,"date":"2019-06-11T16:14:00","date_gmt":"2019-06-11T16:14:00","guid":{"rendered":"https:\/\/associatednews.us\/content\/2019\/06\/11\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv-infections\/"},"modified":"2019-06-11T16:14:00","modified_gmt":"2019-06-11T16:14:00","slug":"expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv-infections","status":"publish","type":"post","link":"https:\/\/associatednews.us\/content\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv-infections\/","title":{"rendered":"Expert Panel Recommends Wider Use Of Daily Pill To Prevent HIV Infections"},"content":{"rendered":"<p><span style=\"font-style:italic;font-size:16px\">By  <a class=\"colorbox\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/06\/11\/731350223\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv?utm_medium=RSS&amp;utm_campaign=healthcare\">Allison Aubrey<\/a><\/span>  <\/p>\n<div class=\"ftpimagefix\" style=\"float:left\"><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/06\/11\/731350223\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv?utm_medium=RSS&amp;utm_campaign=healthcare\"><img decoding=\"async\" width=\"150\" src=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1100-c15.jpg\" alt><\/p>\n<div>\n            <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1200.jpg\"><\/a><\/div>\n<div>\n<div>\n<div>\n            <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1200.jpg\">Enlarge this image<\/a>\n        <\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                In 2012, the Food and Drug Administration approved the use of Truvada to prevent HIV infection in people at high risk.<\/p>\n<p>                <b><\/p>\n<p>                    Justin Sullivan\/Getty Images<\/p>\n<p>                <\/b><br \/>\n                <b><b>hide caption<\/b><\/b>\n            <\/p>\n<\/p><\/div>\n<p>            <b><b>toggle caption<\/b><\/b>\n    <\/div>\n<p>    <span><\/p>\n<p>        Justin Sullivan\/Getty Images<\/p>\n<p>    <\/span>\n<\/div>\n<\/p><\/div>\n<p>The U.S. Preventive Services Task Force has a new recommendation aimed at preventing HIV infections and AIDS. The <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2735509\">influential panel&#8217;s guidance<\/a> says people at high risk of being infected with HIV should be offered preventive antiretroviral medications \u2014 taken in a daily pill.<\/p>\n<p>There&#8217;s lots of evidence that preexposure prophylaxis \u2014 also known as PrEP \u2014 is effective. The Food and Drug Administration-approved pill Truvada contains two antiretroviral medicines (tenofovir and emtricitabine). <\/p>\n<p>The Centers for Disease Control and Prevention cites evidence that <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/risk\/prep\/index.html\">PrEP can reduce the risk of HIV infection by up to 92% <\/a>in people who are at high risk and who take the drug consistently. <\/p>\n<p>The CDC recommended PrEP several years ago and calls it &#8220;<a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/risk\/prep\/index.html\">a powerful HIV prevention tool<\/a>,&#8221; but so far uptake of PrEP has been slow. <\/p>\n<p>&#8220;Currently, less than 10% of individuals with an indication for PrEP are receiving this medication,&#8221; write Hyman Scott and Paul Volberding in an <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2735479\">editorial published Tuesday alongside<\/a> the new recommendation in the medical journal <em>JAMA.<\/em> Both authors are physicians and researchers at the University of California, San Francisco who have been involved in HIV research.<\/p>\n<aside>\n<div><\/div>\n<\/aside>\n<p><!-- END ID=\"RES731649948\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>&#8220;The gap between indication and use is most pronounced among black and Latino men who have sex with men,&#8221; Volberding and Scott write. <\/p>\n<p>And the new recommendation &#8220;should serve to promote policies to expand PrEP access to those at risk,&#8221; they conclude.<\/p>\n<p>People at high risk of HIV infection include those who inject drugs and those who have sex without condoms when they don&#8217;t know the HIV status of their high-risk partner.  <\/p>\n<p>Many insurers already pay for Truvada, but the task force&#8217;s recommendation could be influential in expanding coverage of the drug, whose <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/05\/30\/727731380\/old-fight-new-front-aids-activists-want-lower-drug-prices-now\">list price runs $21,360 a year<\/a>. <\/p>\n<p>&#8220;The cost of the medication is absolutely a barrier for a lot of people in the U.S.,&#8221; Scott said in an interview. &#8220;We have patients who go to the pharmacy and are told they have to pay $1,300 or $1,600 for their month&#8217;s supply of Truvada.&#8221;<\/p>\n<p>Many at-risk people can get the drug at a reduced cost or at no cost, depending on their insurance. &#8220;We try to educate patients to let them know there are many programs to help offset the costs,&#8221; Scott says. <\/p>\n<p>&#8220;We&#8217;ve done a good job in medicine at being able to treat HIV, in the sense it&#8217;s now become a chronic disease for most people &#8230; but we still have a problem with new HIV infections,&#8221; says <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.uspreventiveservicestaskforce.org\/Page\/Biography\/john-w-epling-jr\">John Epling<\/a>, a physician and professor of family and community medicine at Virginia Tech and a member of the U.S. Preventive Services Task Force. The goal is to prevent these infections.<\/p>\n<p>More than <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/statistics\/overview\/ataglance.html\">38,000 new HIV cases were diagnosed <\/a>in the U.S. in 2017, according to the CDC. &#8220;So, we need for primary care clinicians to engage in offering PrEP to their high-risk patients,&#8221; Epling says.  <\/p>\n<p><!-- END ID=\"RES731632637\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The task force&#8217;s recommendation is published with a new review of the evidence, including an analysis of multiple studies evaluating the safety and effectiveness of PrEP.<\/p>\n<p>The studies found that most side effects, including gastrointestinal complaints and some nausea, were mild and reversible. Another side effect in some people taking Truvada is elevated <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/medlineplus.gov\/creatinine.html\">creatinine<\/a>, a measure of kidney function, so patients on the drug are monitored periodically.<\/p>\n<p>The review finds that the therapy significantly reduces the risk of acquiring HIV infection compared with a placebo, although effectiveness drops when people fail to take the pill daily.<\/p>\n<p>&#8220;PrEP is highly effective at preventing HIV acquisition,&#8221; Epling says, &#8220;if it&#8217;s taken every single day and condoms are used.&#8221;<\/p>\n<p><strong><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/\">Let&#8217;s block ads!<\/a><\/strong> <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/acceptable.html\">(Why?)<\/a><\/p>\n<p>Source:: <a href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/06\/11\/731350223\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv?utm_medium=RSS&amp;utm_campaign=healthcare\" class=\"colorbox\" title=\"Expert Panel Recommends Wider Use Of Daily Pill To Prevent HIV Infections\" rel=\"nofollow\">https:\/\/www.npr.org\/sections\/health-shots\/2019\/06\/11\/731350223\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv?utm_medium=RSS&amp;utm_campaign=healthcare<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"ftpimagefix\" style=\"float:left\"><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/06\/11\/731350223\/expert-panel-recommends-wider-use-of-daily-pill-to-prevent-hiv?utm_medium=RSS&amp;utm_campaign=healthcare\"><img decoding=\"async\" width=\"150\" src=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1100-c15.jpg\" alt><\/p>\n<div>\n            <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1200.jpg\"><\/a><\/div>\n<div>\n<div>\n<div>\n            <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/media.npr.org\/assets\/img\/2019\/06\/11\/truvada_gettyimages-107091587_custom-9418edc9e849e512375b6f7340b301d7932f1ea3-s1200.jpg\">Enlarge this image<\/a>\n        <\/div>\n<\/div>\n<div>\n<div>\n<div>\n<p>\n                In 2012, the Food and Drug Administration approved the use of Truvada to prevent HIV infection in people at high risk.<\/p>\n<p>                <b><\/p>\n<p>                    Justin Sullivan\/Getty Images<\/p>\n<p>                <\/b><br \/>\n                <b><b>hide caption<\/b><\/b>\n            <\/p>\n<\/p><\/div>\n<p>            <b><b>toggle caption<\/b><\/b>\n    <\/div>\n<p>    <span><\/p>\n<p>        Justin Sullivan\/Getty Images<\/p>\n<p>    <\/span>\n<\/div>\n<\/p><\/div>\n<p>The U.S. Preventive Services Task Force has a new recommendation aimed at preventing HIV infections and AIDS. The <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2735509\">influential panel&#8217;s guidance<\/a> says people at high risk of being infected with HIV should be offered preventive antiretroviral medications \u2014 taken in a daily pill.<\/p>\n<p>There&#8217;s lots of evidence that preexposure prophylaxis \u2014 also known as PrEP \u2014 is effective. The Food and Drug Administration-approved pill Truvada contains two antiretroviral medicines (tenofovir and emtricitabine). <\/p>\n<p>The Centers for Disease Control and Prevention cites evidence that <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/risk\/prep\/index.html\">PrEP can reduce the risk of HIV infection by up to 92% <\/a>in people who are at high risk and who take the drug consistently. <\/p>\n<p>The CDC recommended PrEP several years ago and calls it &#8220;<a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/risk\/prep\/index.html\">a powerful HIV prevention tool<\/a>,&#8221; but so far uptake of PrEP has been slow. <\/p>\n<p>&#8220;Currently, less than 10% of individuals with an indication for PrEP are receiving this medication,&#8221; write Hyman Scott and Paul Volberding in an <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2735479\">editorial published Tuesday alongside<\/a> the new recommendation in the medical journal <em>JAMA.<\/em> Both authors are physicians and researchers at the University of California, San Francisco who have been involved in HIV research.<\/p>\n<aside>\n<div><\/div>\n<\/aside>\n<p><!-- END ID=\"RES731649948\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>&#8220;The gap between indication and use is most pronounced among black and Latino men who have sex with men,&#8221; Volberding and Scott write. <\/p>\n<p>And the new recommendation &#8220;should serve to promote policies to expand PrEP access to those at risk,&#8221; they conclude.<\/p>\n<p>People at high risk of HIV infection include those who inject drugs and those who have sex without condoms when they don&#8217;t know the HIV status of their high-risk partner.  <\/p>\n<p>Many insurers already pay for Truvada, but the task force&#8217;s recommendation could be influential in expanding coverage of the drug, whose <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2019\/05\/30\/727731380\/old-fight-new-front-aids-activists-want-lower-drug-prices-now\">list price runs $21,360 a year<\/a>. <\/p>\n<p>&#8220;The cost of the medication is absolutely a barrier for a lot of people in the U.S.,&#8221; Scott said in an interview. &#8220;We have patients who go to the pharmacy and are told they have to pay $1,300 or $1,600 for their month&#8217;s supply of Truvada.&#8221;<\/p>\n<p>Many at-risk people can get the drug at a reduced cost or at no cost, depending on their insurance. &#8220;We try to educate patients to let them know there are many programs to help offset the costs,&#8221; Scott says. <\/p>\n<p>&#8220;We&#8217;ve done a good job in medicine at being able to treat HIV, in the sense it&#8217;s now become a chronic disease for most people &#8230; but we still have a problem with new HIV infections,&#8221; says <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.uspreventiveservicestaskforce.org\/Page\/Biography\/john-w-epling-jr\">John Epling<\/a>, a physician and professor of family and community medicine at Virginia Tech and a member of the U.S. Preventive Services Task Force. The goal is to prevent these infections.<\/p>\n<p>More than <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/www.cdc.gov\/hiv\/statistics\/overview\/ataglance.html\">38,000 new HIV cases were diagnosed <\/a>in the U.S. in 2017, according to the CDC. &#8220;So, we need for primary care clinicians to engage in offering PrEP to their high-risk patients,&#8221; Epling says.  <\/p>\n<p><!-- END ID=\"RES731632637\" CLASS=\"BUCKETWRAP INTERNALLINK INSETTWOCOLUMN INSET2COL \" --><\/p>\n<p>The task force&#8217;s recommendation is published with a new review of the evidence, including an analysis of multiple studies evaluating the safety and effectiveness of PrEP.<\/p>\n<p>The studies found that most side effects, including gastrointestinal complaints and some nausea, were mild and reversible. Another side effect in some people taking Truvada is elevated <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/medlineplus.gov\/creatinine.html\">creatinine<\/a>, a measure of kidney function, so patients on the drug are monitored periodically.<\/p>\n<p>The review finds that the therapy significantly reduces the risk of acquiring HIV infection compared with a placebo, although effectiveness drops when people fail to take the pill daily.<\/p>\n<p>&#8220;PrEP is highly effective at preventing HIV acquisition,&#8221; Epling says, &#8220;if it&#8217;s taken every single day and condoms are used.&#8221;<\/p>\n<p><strong><a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/\">Let&#8217;s block ads!<\/a><\/strong> <a class=\"colorbox\" rel=\"nofollow\" href=\"https:\/\/blockads.fivefilters.org\/acceptable.html\">(Why?)<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-20182","post","type-post","status-publish","format-standard","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts\/20182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/comments?post=20182"}],"version-history":[{"count":0,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/posts\/20182\/revisions"}],"wp:attachment":[{"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/media?parent=20182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/categories?post=20182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/associatednews.us\/content\/wp-json\/wp\/v2\/tags?post=20182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}